Emerging Features of Ammonia Metabolism and Transport in Acid-Base Balance

Renal regulation of acid-base balance: ammonia excretion.

tion. The APS Constitution and Bylaws appears in the FASEB Membership Directory. Officers: President, Alfred P. Fishman, University of Pennsylvania Hospital, Philadelphia, PA; President-Elect, John B. West, University of California, La Jolla, CA; Past President, Walter C. Randall, Loyola University, Maywood, IL; Council, Alfred P. Fishman, John B. West, Walter C. Randall, Franklyn G. Knox, Jack...

Effects of feeding on metabolism, gas transport, and acid-base balance in the bullfrog Rana catesbeiana.

Massive feeding in ectothermic vertebrates causes changes in metabolism and acid-base and respiratory parameters. Most investigations have focused on only one aspect of these complex changes, and different species have been used, making comparison among studies difficult. The purpose of the present study was, therefore, to provide an integrative study of the multiple physiological changes takin...

6 Ion Transport , Osmoregulation , and Acid – Base Balance

Acid-base balance and O2 transport at high altitude.

Ear lobe blood pHa, PaCo2, PaO2, and O2 saturation (SaO2) were measured in healthy Caucasians and Sherpas at 3400 m (Namche Bazaar, Nepal, n = 4/5), 5050 m (Pyramid Laboratory, Lobuche, Nepal, n = 20/5) and 6450 m (Camp II of Mt Everest, n = 11/7). In the investigated altitude range, pHa increased progressively with altitude from 7.463 +/- 0.005 (mean +/- SE) to 7.496 +/- 0.006 in Caucasians wh...

Disturbed acid-base transport: an emerging cause of hypertension

Genome-wide association studies and physiological investigations have linked alterations in acid-base transporters to hypertension. Accordingly, Na(+)-coupled HCO(-) 3-transporters, Na(+)/H(+)-exchangers, and anion-exchangers have emerged as putative mechanistic components in blood pressure disturbances. Even though hypertension has been studied extensively over the last several decades, the ca...